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KMID : 0878220080200030164
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Journal of Sasang Constitutional Medicine
2008 Volume.20 No. 3 p.164 ~ p.175
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Anti-aging and Anti-Oxidant Effect of Bopyewon-tang in liver and Lung Cell of SD Rats
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Bae Jung-Kyu
Ahn Taek-Won
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Abstract
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Objective: The purpose of this study is ro investigate the anti-aging and anti-oxidant effects of Bopyewon-tang(BPW) in Liver and Lung cell.
Methods: This experiment was used the tissue of liver and lung cells of 6, 52 and 68 weeks old SD rats. Each age group was again divided into three groups. One group, as normal group, was not-treated cells, another group, as control group, was saline-treated cells, and the last group, as experimental group, was BPW -treated cells. After culture for 48 hours, each groups measured the level of SOD, GSH, MDA and NO in the tissue of liver and lung cells.
Results and Conclusion: 1. The activity of SOD in liver of in 52 w-BPW group, 68 w-BPW group, and in lung of 68 w-BPW were significantly increased in comparison with those of the normal groups. 2. The levels of NO in liver of in 68 w-BPW group was significantly decreased in comparison with those of the normal groups. 3. The levels of MDA in lung of in 68 w-BPW group was significantly decreased in comparison with those of the normal groups.
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KEYWORD
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Bopyewon-tang, Anti-aging Effect, Anti-oxidant Effect, SOD Activity, NO, MDA
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